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Cycloblastin (Cyclophosphamide)
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Cyclophosphamide

Cycloblastin belongs to a class of drugs called alkylating agents. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Cycloblastin works by stopping or slowing the growth or spread of certain cancer cells.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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We examined the psychometric properties of the Japanese version of the Autism Spectrum Screening Questionnaire (ASSQ) and developed a short-form. Racial differences of similar magnitude occur in all types of hospitals. Accurate identification and orientation of the landmark with good understanding of the three-dimensional structure of the prostatic fossa and the detailed technical issues of enucleating along the right capsule plane will be helpful for beginners to overcome the learning curve and gain confidence with this procedure and for experienced surgeons to further improve their surgical technique. CHANGES AND GEOGRAPHIC DISTRIBUTION OF MORTALITY FROM CEREBROVASCULAR DISEASE. The HBNF gene is highly expressed in the neuroepithelium and the ependyma from fetal day 15 on.

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Role of the blood-brain barrier in differential response to opioid peptides and morphine in mouse lines divergently bred for high and low swim stress-induced analgesia. No functional advantages were found in knees implanted with MB prostheses during walking, with both groups indicative of similar differences when compared to normal knee biomechanics following prosthesis implantation.

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The interaction of nucleotides with F1-ATPase inactivated with 4-chloro-7-nitrobenzofurazan. Effect of age on breast cancer outcomes in women with human epidermal growth factor receptor 2-positive breast cancer: results from a herceptin adjuvant trial. In the first experiment 35 chronic schizophrenics and 35 normal controls performed tactile-visual matchings with each hand. To explore the potentially independent effects of HIV-1-related proteins on heart and skeletal muscles, we used a transgenic rat model that expresses several HIV-1-related proteins (e.g., Tat, gp120, and Nef).

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1,25-Dihydroxycholecalciferol (1,25(OH)(2)D(3)) has been shown to mitigate epithelial inflammatory responses after antigen exposure. Our data indicate that Shape Signatures descriptors can be used with SVM and these models may have utility for predicting blood-brain barrier permeation in drug discovery. Effect of co-administration of ketoconazole, a strong CYP3A inhibitor, on the pharmacokinetics, safety and tolerability of navitoclax, a first-in-class oral Bcl-2 family inhibitor, in cancer patients.

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Evaluation of age influence and the effect of iodine value and carbon number. To investigate differences in anterior cruciate ligament-reconstructed (ACLR) and healthy individuals in terms of the magnitude of the tibiofemoral contact forces, as well as the relative muscle and external load contributions to those contact forces, during walking, running, and sidestepping gait tasks.

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Thin-section computed tomography findings before and after azithromycin treatment of neutrophilic reversible lung allograft dysfunction. The present study focuses on species-level phylogeographic patterns of Atraphaxis in China, with the goal of determining the impact of past environmental changes, in northern China, on the evolutionary history of the genus.

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Irritable bowel syndrome (IBS) and chronic idiopathic constipation (CIC) are functional bowel disorders. Extra steps may be necessary to ensure optimal outcomes for people with ID. For the unsynchronized case, some special cell-site engineering techniques may be required to reduce the ACI. Each gene identified so far accounts for a small percentage of all NTD cases, indicating a very high heterogeneity. Structural and functional analysis of the regulatory sequences of the ets-1 gene.

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Family conferences are an essential component of high-quality ICU care and an important skill for physicians. We investigated if serum expression of chitinases and IgE early after WTC exposure predicts subsequent obstruction.

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Housing, the Neighborhood Environment, and Physical Activity among Older African Americans. Selective bronchial intubation in patient with tracheobronchial alterations. The methylation status of miR-124a seen in this study concurs with that reported in tumor cells, indicating epigenetic dysregulation constituents, a mechanism in the development of rheumatoid arthritis. The structure provides a rationale-Lys35 compensates for the co-factor site mutation. Hereditary protein C deficiency and thrombosis risk: genotype and phenotype relation in a large Italian family.

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The increasing number of discovered and/or engineered fluorescent proteins with unique absorbance/emission spectra, combined with the growing number of detection devices and lasers, increases multiplexing versatility, making fluorescent genetic barcoding a powerful tool for flow cytometry-based analysis. Using image-based transcriptomics in millions of single human cells, we find that while variability of cytoplasmic transcript abundance is large, it is for most genes minimally stochastic and can be predicted with multivariate models of the phenotypic state and population context of single cells. We were unable to assess the effects of mood stabilizer dose on brain structure. Autophagy is an inducible intracellular process acting under stressor conditions, such as infections, inflammation and hypoxia. Economic burden of dermatologic adverse events induced by molecularly targeted cancer agents.

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Time for a breath of fresh air: Rethinking training in airway management. The retention of an inhibitory avoidance response was also evaluated in response of the same treatments. The proportion loss of infection was relatively higher in microfilaria carriers who discontinued DEC selective therapy, when compared to natural loss. To determine the effectiveness of management strategies for sexual dysfunction caused by antidepressants.2. These include central purchasing, establishment of a National control authority and local vaccine production.

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Effect of ethylene oxide sterilization and storage conditions on canine cortical bone harvested for banking. The influence of pyrogen habituation (tolerance) on the distribution of a marked endotoxin in the organism They recovered full muscle power after operation and resumed pitching training. Harm ratings of substances help in understanding the perception toward substance use and formulating policies.

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Prevention of release could be a mechanism for regulation of bFGF activity and may be a consequence of the apparent absence of a secretory-signal sequence in the bFGF protein. A new experimental approach of the Kolsky bar system using optical interferometry is presented for determination of dynamic behavior of materials.

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Next-generation sequencing adds value to the preoperative diagnosis of pancreatic cysts. At liquid nitrogen temperature, illumination induced a rise of the fluorescence yield and a complete photooxidation of P-700 in the ascorbate-treated sample.

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Autophagy induction in tobacco leaves infected by potato virus Y(O) and its putative roles. Isotonic saline solution is recommended for infusions, and routine administration of sodium bicarbonate is not recommended. To evaluate intrarenal arterial stiffness by Doppler ultrasound and examine the correlation between renal Doppler indices, glomerular filtration rate, and digital microvascular damage in systemic sclerosis patients. The four derived NPCs showed a significantly higher expression of nestin than was shown by the negative control.

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Structure elucidation of acid reaction products of indole-3-carbinol: detection in vivo and enzyme induction in vitro. A mixture of human lipoaspirate and normal saline (1:100, 0.2 mL) was injected into the external jugular vein of rats, weighing 200 g on average. No evidence has been obtained to suggest that the formation of this compound would present a hazard to the stability of standards prepared by the procedures customarily employed.

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We propose a principled approach for unblocking these reactions and extend it to the problems of identifying essential and synthetic lethal reactions and minimal media. The Added Value of Assessing Ligand-Receptor Binding Kinetics in Drug Discovery. Usability evaluation with mental health professionals and young people to develop an Internet-based cognitive-behaviour therapy program for adolescents with anxiety disorders.

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To evaluate the performance of F-ELISA in diagnosis of schistosomiasis, the detection accuracy of F-ELISA was compared with routine ELISA and dipstick dye immunoassay (DDIA) by testing serum samples from both healthy subjects and those clinically diagnosed with schistosomiasis and clonorchiasis in parallel. As a result, the QCM responses only depend on the solution concentration changes during the crystallization. No significant differences in enzyme-linked immunosorbent assay reactions were detected in sera of M.

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An unhealthy body mass index (BMI) has been associated with depression but the direction of association is uncertain. The objective of this study was to investigate the role of grafted oral keratinocytes in a transplanted ex vivo-produced oral mucosa equivalent (EVPOME) in the regeneration and/or healing process of the oral mucosa at the recipient site. Furthermore, we demonstrate that the functional may be applied for the study of vesicles in a continuum field description. Identification of mechanisms of action of bisphenol a-induced human preadipocyte differentiation by transcriptional profiling. Model curation involves determining metabolite protonation status or charge, ensuring that reactions are stoichiometrically balanced, assigning reactions to appropriate subcellular compartments, deleting generic reactions or creating specific versions of them, linking dead-end metabolites, and filling of pathway gaps to complete the model.

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Clinical, epizootological, and laboratory data for 9 endemic foci of hemorrhagic fever with renal syndrome (HFRS) were compared. Under several pathophysiological conditions thromboxane (TX) could be an important factor for the genesis of cardiac arrhythmias. Mixing of the internal aqueous compartments of liposome was established using the terbium fluorescence technique.

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The following review article explores the available evidence and describes future developments for its use in trauma and orthopaedic practice. Evaluating the prognostic significance of preoperative thrombocytosis in epithelial ovarian cancer.

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Patients with axial SpA already have impaired quality of life and physical function, albeit mildly, at the beginning of their disease course. Macroautophagy (hereafter autophagy) is currently one of the areas of medical life sciences attracting a great interest because of its pathological implications and therapy potentials.

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