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In borderline patients, characterized by a high basal cardiac output (CO), plasma levels were always lower than in permanent hypertensives. Results suggest that rituximab induction as a standard immunosuppression protocol may have a preventive effect for dnDSA production in the non-HLA sensitized low immunologic risk patients. Treatment of mutant p53-expressing cancer cells with RETRA results in a substantial increase in the expression level of p73, and a release of p73 from the blocking complex with mutant p53, which produces tumor-suppressor effects similar to the functional reactivation of p53. EFFECTS OF LIGATION AND MORPHINE ON ELECTRIC AND MOTOR ACTIVITY OF DOG DUODENUM.

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The pore structure of the obtained polymer foams was observed by field-emission scanning electron microscopy (FE-SEM). Dental implant success rates for each type of flap were compared at 1-year intervals for 5 years. Medical, nursing, psychological, social science and grey literature databases, bibliographies, hand-searches and contact with authors. Vasoconstrictor response to phenylephrine was measured before and after insulin injection in 10 diabetics. Computer-assisted semen analysis (CASA) of epididymal sperm from the domestic cat.

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The killer strains are able to kill other microbes occupying the same ecological niche, and do so with impunity. High-quality preoperative imaging and mastery in surgical expertise are requirements for identification and preservation of aberrant hepatic arterial anatomy during procedures involving vital intra-abdominal organs. Placental restriction in multi-fetal pregnancies increases spontaneous ambulatory activity during daylight hours in young adult female sheep. The distributions of field placement errors were similar to those in a published study of straight edged fields. Past, Present and Future: The Outlook from Mid-Career Nurse Informaticians.

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Extended RAS analysis was performed on 227 wild-type KRAS exon 2 mCRC patients who received cetuximab as salvage treatment using OncoMap ver. Galactose-fed chicks have been found to develop severe hyperosmolar dehydration. This study aimed to 1) evaluate arterial distensibility and echocardiographic measures in adolescent smokers before and after participation in a successful smoking cessation program and to 2) compare the findings obtained with data from a control population of healthy non-smokers. Reflecting this regulatory complexity, the length of each phase varies considerably in different kinds of cells but also among genetically and morphologically indistinguishable cells. The juvenile plants also showed a significant ploidy by elevation interaction, indicating that diploids and tetraploids survived best at their native elevations.

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Although such efforts were initiated more than half a century ago, no safe and effective radiation countermeasure has been approved by the United States Food and Drug Administration (FDA) for the acute radiation syndrome. The role of the nerve supply in this adaptation has been investigated using denervated muscles and muscles from dystrophic animals where there is thought to be an abnormality of the nerve supply.

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Nulliparity and infertility were associated with an increased risk, and multiparity with a reduced risk, of benign epithelial ovarian neoplasms. Seventeen pediatric patients with AN who received a CI and a group of children with CoHL who received a CI were the subjects of this study. Direct voxel-based comparisons between grey matter shrinkage and glucose hypometabolism in chronic alcoholism.

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TCAP knockdown by RNA interference inhibits myoblast differentiation in cultured skeletal muscle cells. Care should be taken when stratifying COPD patients with one symptom scale versus another according to the GOLD 2011 document. More well controlled clinical intervention trials are needed to further clarify the exact role of lycopene in the prevention of lung cancer cell growth. Human leukocyte antigen (HLA) DR1 was associated with the development of multiple BCCs in people under the age of 55, but not in older people. Isolation and functional analysis of CONSTANS-LIKE genes suggests that a central role for CONSTANS in flowering time control is not evolutionarily conserved in Medicago truncatula.

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Evolution of Neuroadaptation in the Periphery and Purifying Selection in the Brain Contribute to Compartmentalization of Simian Immunodeficiency Virus (SIV) in the Brains of Rhesus Macaques with SIV-Associated Encephalitis. Our results suggest that the transient expression of N-myc and c-myc oncogenes during the prereplicative stage of liver regeneration may be associated with the entry of hepatocytes into the cell cycle, and that N-myc expression is not limited to tumors of neural characteristics as has been previously shown but is also observed in cancer from epithelial origin. PolyP significantly increases the rate of interaction between C1s and C1-INH, to an extent comparable to heparin, with an exosite on the serine protease domain of the enzyme playing a major role in this interaction. Human-mouse cell hybrids: a suggestion of structural mutation for dipeptidase-2 deficiency in mouse cells.

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Expert Knowledge for Modeling Functional Health from Sensor Data. Cases of successive and simultaneous nuclear differentiation are defined, and examples from various groups of protozoa are considered. The results of fluorescence measurements on the tubulin-bound analogue are reported. They are of irregular outline, and the larger sacs tend to be located in the base of the cells. In critically ill patients, dosing of unfractionated heparin (UFH) is difficult due to unpredictable pharmacokinetics, which has an impact on the time to reach therapeutic anticoagulation.

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Moreover, they provide a singular example of how gene ancestry can impact expression timing. In 32 patients with femoral neck fractures complicated with CRF, we evaluated how the timing of the surgery determines the mortality rates if the DCO approach is applied. The latter part deals with the basic physical and biochemical functions of fat-soluble vitamins, namely, vitamin A, vitamin D, vitamin E and vitamin K. Taken together, these results provide a deeper understanding of the physicochemical properties of CagA that underpin its complex cellular and oncogenic functions. Our data suggest that further studies regarding the suitability of MM-121 for treatment of breast cancer patients whose tumors overexpress erbB2 and become resistant to trastuzumab may be warranted.

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Our secondary outcome measures were improvement in psychological status or quality of life, decrease in fatigue, increase in, or reduction in rate of decline of muscle strength (strengthening or resistance studies), increase in, or reduction in rate of decline of aerobic endurance (aerobic or endurance studies) at three months and frequency of adverse effects. On the effect of tryptic enzymes on the virus of myeloid leukemia in the mouse It was hypothesized that field-dependent persons would be reasoning at the conventional level, whereas field-independent persons would reason at the post-conventional level. A Depleting Anti-CD45 Monoclonal Antibody as Isolated Conditioning for Bone Marrow Transplantation in the Rat.

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Determination of MIC distribution of arbekacin, cefminox, fosfomycin, biapenem and other antibiotics against gram-negative clinical isolates in South India: a prospective study. A goal in our current research is to develop new compounds that recognize mixed sequences of DNA. Vaginal challenge with an SIV-based dual reporter system reveals that infection can occur throughout the upper and lower female reproductive tract. Biceps tenodesis performed with our Needle-Anchor technique applied to selected patients affected by isolated LHB pathology demonstrated to be effective both in terms of pain and functionality.

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In Vitro and In Vivo Assessment of Angiotensin-Converting Enzyme (ACE) Inhibitory Activity of Fermented Soybean Milk by Lactobacillus casei Strains. An evaluation of an Australian initiative designed to improve interdisciplinary collaboration in primary mental health care. The CCHCC model was designed to enable children who would otherwise remain hospitalized at a substantial cost to third party payers to move home, providing a humane choice for families while requiring less costly care for funders. Moreover, it is not only applicable for ultrastructural examinations but it can also be combined with immunogold labelings for protein localization investigations.

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To determine the heritability of spine curve using plain radiographs and to identify risk factors for spine curvature including age, body mass index, smoking, bone mineral density (BMD), and lumbar disc degeneration (LDD). In nulliparous low-risk women a larger infant head circumference at birth increases the likelihood of perineal trauma, although the effect is modest. As a causative agent of hypercalcemia in ATL, tumor necrosis factor-beta (TNF-beta), previously known as lymphotoxin, has been carefully studied and reviewed here.

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Primary medial sphenoid ridge tumors consistently involve the unilateral arteries of the anterior cerebral circulation, and therefore, the resection of tumor from around these arteries is the most important operative nuance for their safe excision. Fanconi anemia (FA) is a genome instability syndrome that is characterized by progressive bone marrow failure and a high risk of cancer. We investigated the association between serum DPP-4 levels and visceral fat area as well as the presence of metabolic syndrome. In contrast to previous studies, the WI meal caused a decreased rate of gastric emptying compared to the other test meals. Since 2007 an increasing number of prostate cancer centers have been guided toward certification by the OnkoZert GmbH of the GCS.

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(i) In intact subjects, repeated stimulation with bright light causes a predictable change (alpha blocking) in the electroencephalogram, whereas repeated auditory stimulation does not. Endocytosis of glycophospholipid-anchored and transmembrane forms of CD4 by different endocytic pathways.

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These include the amide nitrogen of glutamine, the alpha-amino nitrogens of glutamate and other amino acids, the guanidino nitrogens of arginine, the ureido nitrogen of citrulline, the side-chain nitrogens of ornithine or lysine, or both, and uridine diphosphates. Peripheral ligand-binding site in cytochrome P450 3A4 located with fluorescence resonance energy transfer (FRET).

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Moreover, UDCA scavenged the reactive oxygen species (ROS), increased the membrane potential, and inhibited apoptosis in AGS cells exposed to H(2)O(2) in vitro through the mitochondria-mediated pathway. This soil data-induced error would be inevitably magnified from the flow simulation to the NPS prediction stage.

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Transmission between seawater sites occurs mainly passively by water currents or actively through human activity coupled with inadequate biosecurity measures. Authors stress the importance of the conservative management of spleen injuries, to preserve its hematologic and immunologic functions. Tissue specificity in the nuclear envelope supports its functional complexity. Additionally, differences in temporal and strain specific gene expression can also contribute to phenotypes in the mammalian retina. Correlations with serum lipid levels, adiposity, and serum insulin level.

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Learning impairments in children consist of a spectrum of disorders that are under diagnosed in Pakistan. This new technique achieves the objectives described (no increases in ischemic time, fewer vascular complications).

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More recent studies have demonstrated not only that the long term emotional costs of head injury are enormous for survivor and family members, but the functional consequences in terms of changes in family life, recreational and vocational activities, are great and prolonged. Binding of ADP favored Rep dimers in which both protomers bound single-stranded DNA, whereas binding of AMPP(NH)P favored simultaneous binding of both single-stranded and duplex DNA to the Rep dimer. The obtained results were in agreement with previously reported findings. A select group of willow clones was analyzed using high-resolution thermogravimetric analysis (HR-TGA), and significant differences in biomass composition were observed.

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Punishment by blinding, though of extremely ancient origin, was imposed on Christians in the Roman Empire under the rule of Diocletian (AD 303). Swedish isolates of Vibrio cholerae enhance their survival when interacted intracellularly with Acanthamoeba castellanii. This study was designed to evaluate the clinical role of rHuEPO in reducing symptomatic anemia in patients with advanced cancer who were receiving myelosuppressive chemotherapy (excluding cisplatin). In this paper we introduce and apply a strategy to extend this dynamic range for affinity sensors, sensors which measure the amount of hybridized molecules after equilibrium is reached.

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Inducing ovulation early postpartum influences uterine health and fertility in dairy cows. Participation in a comprehensive simulation-based training curriculum for gynecologic laparoscopy leads to a superior improvement in knowledge and technical performance in the operating room compared with conventional residency training. Frameless stereotactic drilling for placement of depth electrodes in refractory epilepsy: operative technique and initial experience. The muscularis propria of the esophagus is organized into circular and longitudinal muscle layers. Brief report: a phase IIa, randomized, double-blind, placebo-controlled trial of apilimod mesylate, an interleukin-12/interleukin-23 inhibitor, in patients with rheumatoid arthritis.

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Besides the degree of valvular involvement, the prognosis relies crucially on the presence of systemic infectious embolism. Although additional studies on the participation of IL-6 in RA physiopathology are needed, a number of indirect data point to a relevant position in this setting. Colour in the eye of the beholder: receptor sensitivities and neural circuits underlying colour opponency and colour perception. The yield of HB-GAM is increased by 5- to 10-fold when 250 mM NaCl is added to the homogenization buffer, indicating that HB-GAM may exist as a complex with an insoluble component of the tissue. Abnormal collections of mitochondria in nerve and muscle as well as diffuse white matter disease were present.

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The intradermal injection of endothelin-1 (10 pmol) into human skin induced a pallor with surrounding axon-reflex flare which is similar to the flare response to histamine (1 nmol). Pemphigus, defines a group of disorders in autoimmune etiology which could be life-threatening and clinical manifestations are mainly epithelial blistering affecting cutaneous and/or mucosal surfaces including oral mucosa.

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The present study shows how to create the artificial enzymes with excellent optical properties for bioassays and encourages researchers to fabricate their own unique artificial enzymes with designed properties and functionalities. Oxidative modifications of protein can be easily found in protein-rich food such as meat and milk products. Disseminated tuberculosis with splenic tuberculosis abscess rupture.

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fEPSPs and population spikes (PS) were recorded at 5, 30, and 60min after HFS in order to measure changes in the synaptic responses of DG neurons. Different analytical and chemometric platforms are necessary to detect as many metabolites as possible in different biological fluids. Recent advances in late lung development and the pathogenesis of bronchopulmonary dysplasia. albicans in agar dilution test, at a concentration of 1/2 MIC caused a drop in the value of fluconazole MIC from 12.0 mg/l to 0.064 mg/l and voriconazole from 0.125 mg/l to 0.006 mg/l. In Wilson disease (WD), the copper content of cerebral tissue is increased, particularly in the basal ganglia.

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Despite the fact that Italian nurses have only recently gained autonomy when making health-care decisions, there is little evidence available regarding the decisions actually taken in clinical practice. Improving access and input to personal health information is still in its infancy, but with government funding, development of patient health records will continue to grow.

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It is shown that if the SRRs are placed with the slits aligned with the symmetry plane of the CPW, the structure is transparent to signal propagation. An open-label, multicentre, randomised, dose-finding study lasting six cycles in healthy women aged 18-35 years was used. is extraordinarily flexible, being C(3)/CAM intermediate and expressing the photosynthetic modes C(3), CAM, CAM-cycling, and CAM-idling.

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Spectroscopic characterization, antioxidant and antitumour studies of novel bromo substituted thiosemicarbazone and its copper(II), nickel(II) and palladium(II) complexes. Due to their more widespread availability and the potential benefits of improved hemostasis and wound healing, their use during facial plastic and reconstructive surgery procedures has also grown. The sipuleucel-T manufacturing process, toxicity and clinical benefit are reviewed, along with an examination of the issue of clinical benefit to survival, independent of apparent changes of prostate-specific antigen (PSA) levels.

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Anticonvulsant effects of intracerebroventricularly administered norepinephrine are potentiated in the presence of monoamine oxidase inhibition in severe seizure genetically epilepsy-prone rats (GEPR-9s). This study demonstrates that children with CD on a GFD for a year have a much higher prevalence of functional GI symptoms than do controls. Medical history and information on past-year hospital visits for 8,089 adult residents were obtained from interviews with RCF staff. Photon statistics of resonance fluorescence in the limit of separated spectral lines.

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We were unable to remove the cysts without rupturing them because they were tightly surrounded. All the children were asymptomatic and physical examination was completely normal. Investigation of polycyclic aromatic hydrocarbon content in fly ash and bottom ash of biomass incineration plants in relation to the operating temperature and unburned carbon content.

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Experimental studies have reported that glycine is adsorbed on the Cu(110) and Cu(100) surfaces in its deprotonated form at room temperature, but in its zwitterionic form on Pd(111) and Pt(111). Behavioural alterations are independent of sickness behaviour in chronic experimental Chagas disease. Pharmacological management of breathlessness in COPD: recent advances and hopes for the future. A biochemical and cytological investigation of differentiation in the interspecific hybrid amphibian embryo Rana pipiens female x Rana sylvatica male. Cleavage of C3 by neutral proteases from granulocytes in pleural empyema.

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Clinical FeNO measurement is a simple, noninvasive, and rapid method used to differentiate asthmatic from nonasthmatic patients with BE. Strategies for improving antimicrobial use and the role of antimicrobial stewardship programs. Anterior cervical discectomy and fusion (ACDF) has long been the preferred treatment for cervical radiculopathy and myelopathy. Finally, recent data suggest that osteoclasts may be capable of antigen presentation to T cells via major histocompatibility complex class I and class II molecules.

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The patients were treated with amoxycillin (2 g/day for 2 months) associated with metronidazole (750 mg/day for 15 days), which reduced the symptoms dramatically. Neuroanatomy of the killer whale (Orcinus orca): a magnetic resonance imaging investigation of structure with insights on function and evolution.

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The causes of vaccine hesitancy varied in the different countries and were context-specific, indicating a need to strengthen the capacity of national programmes to identify the locally relevant causal factors and to develop adapted strategies to address them. We propose that ligand induced conformational changes generally operate in this viscoelastic regime, and that this is a universal property of the folded state. mHealth Pilot Study: Text Messaging Intervention to Promote HPV Vaccination. With challenges of over 300 LD(50) no treatment was of any value.