Toplep is an oral drug that is used to prevent the seizures of epilepsy. It is an anti-epileptic or anti-seizure drug. It is used primarily among patients who are not controlled by other anti-epileptic drugs. About 1 in 4 Americans diagnosed with epilepsy has seizures that resist treatment with other anti-epileptic drugs. Toplep also prevents migraine headaches. Seizures are due to the abnormal activity ("firing") of nerves in the brain, and the abnormal activity spreads to smaller or larger portions of the brain. Although Toplep's exact mechanism of action is unknown, scientific studies suggest that it may alter neurotransmitters within the brain. Neurotransmitters are chemicals that nerves manufacture and use to communicate with other nearby nerves. By altering the production or action of the neurotransmitters, Toplep may suppress the abnormal activity of the nerves in the brain that cause the seizures or may prevent the abnormal activity from spreading to other nerves. Other studies suggest that Toplep may suppress the nerves directly (i.e., not by altering neurotransmitters) and make them less likely to fire. The FDA approved Toplep as a tablet in 1997. The sprinkle capsules were approved in October 1998.
Other names for this medication:
Topiramate,
Topamax,
Epitomax,
Letop,
Neutop,
Piramax,
Talopam,
Topamac,
Topictal,
Topigen,
Topilex,
Topimax,
Topina,
Topiramato,
Topirol,
Toplep,
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