Zemyc is a synthetic compound known as a bis-triazole. It was first used in patients 1994/95 and licensed for use in 1990. It went off patent in 2003. It works by inhibiting the production of ergosterol, a central chemical in the cell walls of fungi. The drug is available as a capsule, oral suspension and intravenous infusion. A typical dose for oral thrush is 100mg per day. The typical dose for vaginal thrush is a 150mg per day. For the prevention of fungal infections in leukaemia, doses from 50-400mg per day have been used and studied. Most authorities recommend between 100 and 400mg. For the treatment of candidemia and other serious Candida infections a minimum dose of 400mg per day (after a loading dose of 800mg) is recommended with increased doses in patients on haemofiltration and/or rifampicin (see below). Some authors have suggested that 800mg is superior for candidaemia, but the data is not compelling. For the treatment of cryptococcal meningitis after amphotericin B, a minimum of 400mg per day initially is used until the patient is stable and then typically 200mg per day. Much larger doses e.g. 800-1200mg per day should be used as an alternative primary regimen (preferably with flucytosine) or for patients failing therapy. Larger doses such as 800-1200mg per day have been used for coccidioidal meningitis. Almost all other treatments have been for 100-400mg per day. Reduced doses may be appropriate in severe renal dysfunction.
Other names for this medication:
Fluconazole,
Diflucan,
Afumix,
Afungil,
Batacan,
Candidin,
Diflazon,
Difluzol,
Difluzole,
Dizole,
Dofil,
Duracan,
Efac,
Elazor,
Exomax,
Farzul,
Fluc,
Flucomed,
Flucon,
Fluconapen,
Fluconazol,
Flusenil,
Flutec,
Fluvin,
Fluzol,
Fluzole,
Fluzone,
Forcan,
Govazol,
Honguil,
Ibarin,
Kifluzol,
Lavisa,
Logican,
Lucon,
Medoflucon,
Novacan,
Omastin,
Ozole,
Ponaris,
Rifagen,
Sacona,
Stabilanol,
Syscan,
Ticamet,
Trican,
Triflucan,
Trizol,
Uzol,
Varmec,
Zemyc,
Zolax,
Zoldicam,
Zolen,
Zoloder,
Zucon,
Similar Products:
Progut,
Sepram,
Aloc,
Veldona,
Lanfast,
Talopam,
Ketovid,
Ocid,
Daktagold,
Prozac,
Virolex,
Dumocycline,
Ulcratex,
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Rulide,
Soltrim,
Miracid,
Pegasys,
Venlalic,
Zosec,
Llanol,
Topamax,
Miravirsen,
Oxicodal,
Pantium,
Cefdinir,
Clindamycine,
Ucerax,
Labileno,
Chibroxin,
Verisan,
Metacycline,
Omepren,
Emimycin,
Amoksycylina,
Faxine,
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Metronex,
Zolt,
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Esoral,
Omastin,
Lamzid,
Pehatrim,
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